The Cortez brothers rob a bank and flee beyond the Mexican border. On their trail are various people, each for a different reason: Sheriff Fulton is sent by the robbed bank to recuperate the money; Django, a head-hunter, is after them for the reward money; Pickwick is after a saddle stolen from him by the Cortez brothers; Pedro and Dolores, saloon owners, also would like to have the loot.

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