UFC 260: Miocic vs. Ngannou 2 was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on March 27, 2021 at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A UFC Heavyweight Championship rematch bout between current two-time champion Stipe Miocic and Francis Ngannou headlined this event. The pairing met previously at UFC 220 on January 20, 2018, where Miocic won via unanimous decision and broke the record for most consecutive title defenses for the division with his third.

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